Clinical and Medical Case Reports

Department of Pharmacy, Ibn Sina Hospital, Ibn Sina University Hospital, Rabat, Morocco

Publications

• Case Report   
  Hepatic Cytolysis Induced by Percutaneous Application of Atractylis Gummifera: About a Case
  Author(s): Oumaima El Qabissi*, Asmaa Alaoui Mdaghri, Yamna Kriouile and Aicha Chaibi
  
  Object: The thistle is an herbaceous plant known for its toxicity; it contains two diterpenic heterosides the Atractyloside and the carboxyatractyloside, which are mitochondrial poisons, disrupting cellular respiration. The clinical manifestations of thistle poisoning are digestive, neurological and hematological disorders. But there are also mild forms of poisoning. We report the case of a 9 month old female infant with no personal and family medical pathological history, admitted to the PII service in a table of jet vomiting associated with consciousness disorders and hypoglycaemia, the biochemical assessment found hepatic cytolysis. The history revealed the notion of local administration of thistle in powder form on diaper rash of the infant. The outcome was favorable with symptomatic treatment based on N-acetyl cysteine. Conclus.. Read More»
  DOI: 10.37421/2684-4915.2023.6.249

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