Veterinary Science & Technology

Department of Veterinary Science, Nepal Polytechnic Institute, Bharatpur, Chitwan, Nepal

Publications

• Case Study   
  Clostridium Associated Necrotizing Hepatitis with Multiple Organ Lesions in a Dog
  Author(s): Ayush Adhikari* and Dinesh Kumar Singh
  
  Clostridium-associated necrotizing hepatitis with multiple organ lesions is a rare and severe condition in dogs. Clostridium species, anaerobic bacteria commonly found in the environment, can lead to various infectious diseases in animals. Among these, Clostridium novyi type B has been identified as a causative agent of necrotizing hepatitis. This case study presents a 4.5-year-old spayed female Golden Retriever with acute-onset lethargy, decreased appetite, and vomiting. Post-mortem examination revealed liver lesions consistent with Clostridium-associated necrotizing hepatitis and significant pathology in the kidneys, heart, and spleen, indicating multi-organ involvement. Histopathological examination further supported the diagnosis, highlighting panlobular hepatocytic necrosis, endospore forming bacilli, and toxin-related damage. While the pathophysiology underlying this condition r.. Read More»
  DOI: 10.37421/2157-7579.2024.15.235

  Abstract HTML PDF