Aragon Health Service, Zaragoza, Spain
Short Communication
Cancer: Stress and PAI-1
Author(s): Lasierra-Cirujeda J*, Aza-Pascual-Salcedo MJ, Aza-Pascual-Salcedo MM, Lasierra-Ibañez A and Lasala-Aza C
Cancer is a group of diseases that are characterized by the development of abnormal cells, which divide almost
without limit, develop, spread without control anywhere in the body, losing the cells their ability to disappear by
an anti- apoptotic action, essential process for malignant transformation and tumor development. The onset and
development of cancer is associated with multiple causes and predisposing factors such as stress and psychosocial
factors PAI-1 is a gene regulated by stress and is paradoxicallyinteracted in close relation with uPA in the development
of tumors... Read More»
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