Department of Biochemistry, Slovak University of Technology in Bratislava, Bratislava, Slovakia
Mini Review
Modern Synthesis of Triflamides and Triflimides
Author(s): Bennett Ramky*
N-Trifluoromethanesulfonamides (CF3SO2NHR, TfNHR) have found extensive use in natural union over the past two decades as reagents, catalysts,
additives, and substituents that alter reactivity and organic movement in a variety of substrates. Early surveys on the subject of triflamide and
its subordinates were conducted, which supports the enormous interest in such constructs. Triflamides are among the most grounded NH- acids
since they have significant areas of strength for a pulling out CF3SO2 bunch in their design (pKa (in H2O) for TfNH2 is 6.33, pKa (in H2O) for Tf2NH
is 2.8). This characteristic determines how triflamides are used in natural blends, in the production of pharmaceutically and organically active
chemicals, as well as in various industries... Read More»
DOI:
10.37421/2150-3494.2022.13.324
Chemical Sciences Journal received 912 citations as per Google Scholar report