Copenhagen University, Denmark
Short Communication
Global Dermatology 2018 -Topical Nutlin-3 Potentiates the UVB-induced p53 Response and Reduces DNA Photodamage and Apoptosis in Mouse Epidermal Keratinocytes in Vivo- Birthe Mørch Thomsen- Copenhagen University
Author(s): Birthe Mørch Thomsen
Background/Aims: (-)-Nutlin-3 (nutlin) may be a cis-imidazoline analog, which activates p53 by antagonizing murine double minute (Mdm2) protein. We therefore conducted a study in hairless mice to analyze the effect of topical nutlin on murine epidermis after UVB-radiation.
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Research and Reports in Medical Sciences received 13 citations as per Google Scholar report