Molecular and Genetic Medicine

Director of the Research Department, Genesis Foundation, Colombia

Publications

• Research Article   
  Chlorine Dioxide in COVID-19: Hypothesis about the Possible Mechanism of Molecular Action in SARS-CoV-2
  Author(s): Eduardo Insignares-Carrione*, Blanca Bolano Gómez and Andreas Ludwig Kalcker
  
  Introduction: The aim of this review is to hypothesize the mechanism of action of chlorine dioxide in COVID-19 by studying its mechanism of action in the structure of SARS-CoV-2. Methods: Reviews of research on the mechanism of action of chlorine dioxide in viruses, particularly SARS-CoV-2and influenza viruses at the amino acid level in the viral spike were conducted and these data were transferred to the same structural amino acids of SARS-CoV-2. We used 3D computer reconstructions, use of data through cryo-electronic studies, and previous work based on ChimeraX (UCSF) augmented reality software. Results: The projection and simulation of chlorine dioxide oxidation in structural amino acids of SARS-CoV-2 allows inferring the sites in which chlorine dioxide exerts a denaturalizing action on viral structure a.. Read More»
  DOI: 10.37421/1747-0862.2020.14.468

  Abstract HTML PDF