University of Medicine and Pharmacy of Târgu Mureş, Târgu Mureș, Romania
Short Communication
The Role of Menin in the Thyroid Lesions
Author(s): Capraru Oana Maria*
Multiple Endocrine Neoplasia type 1 is a hereditary syndrome, with an autosomal dominant transmission, characterized by hyperplasia/ tumours in endocrine organs
(parathyroids, pituitary, gastro-intestinal system). The gene involved is MEN1 gene on chromosome 11q13 which encodes menin, an oncosuppressive nuclear protein
according to Knudson “two hit” hypothesis. Expression of menin and its inactivation in the thyroid gland have long been debated... Read More»
DOI:
10.37421/2684-4265.2020.4.130
Journal of Morphology and Anatomy received 63 citations as per Google Scholar report