Department of Pharmacy, Brandon University, 270 18th St, Brandon, MB R7A 6A9, Canada
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Impact of Polymorphism and Particle Size on the Bioavailability of Active Pharmaceutical Ingredients
Author(s): Carlos Lorena*
Bioavailability is a critical factor in the efficacy of Active Pharmaceutical Ingredients (APIs). Two key physical properties influencing bioavailability are polymorphism and particle size. Polymorphism refers to the ability of a compound to exist in more than one crystalline form, while particle size impacts the dissolution rate and, consequently, the bioavailability of the API. This article explores the mechanisms by which polymorphism and particle size affect bioavailability, supported by recent research and case studies... Read More»
DOI:
10.37421/2577-0543.2024.8.208
Journal of Formulation Science & Bioavailability received 23 citations as per Google Scholar report