Department of Industrial Engineering and Management, Taipei, Taiwan
Research
Combined TACE and Radiotherapy Treatment for Patients with
Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis
Author(s): Pi-Yi Chang, Jen-I Hwang, Jau-Shin Hon* and Chen-Yang Cheng
Objective: To evaluate the clinical effectiveness of a combined treatment consisting of local radiotherapy (external beam radiotherapy, “EBRT”) and transarterial chemoembolization (TACE) for patients with advanced liver tumors with portal vein tumor thrombosis and to identify independent prognostic factors for such patients.
Patients and Methods: From March 2006 to December 2014, 96 patients with unresectable HCC complicated by PVTT were recruited as cases. All subjects received TACE and EBRT. Patient survival was estimated by Kaplan-Meier analysis. In multivariate analyses, the risk of patients’ mortality was estimated by hazard ratio (HR) in Cox proportional hazard regression model.
Results: Mean overall patient survival was 14.8±0.9 months, with 1-year and 2-year survival rates of 40.6% .. Read More»
DOI:
10.37421/2329-6771.2022.11.362
Journal of Integrative Oncology received 495 citations as per Google Scholar report