Department of Molecular Genetics, University of Cantabria, Santander, Cantabria, Spain
Mini Review
The Use of Recombinant PrP in Research Concerning Transmissible Spongiform Encephalopathies
Author(s): Chloe Harrington*
Transmissible Spongiform Encephalopathies (TSEs) are a group of fatal neurodegenerative diseases affecting both humans and animals. The
underlying cause of these disorders involves the misfolding and aggregation of the Prion Protein (PrP). Investigating the mechanisms behind
TSEs requires a deep understanding of PrP's structure and function. Recombinant PrP technology has emerged as a pivotal tool in TSE research,
offering precise control and manipulation of PrP variants. This article delves into the significance and applications of recombinant PrP in unraveling
the complexities of TSEs, highlighting its contributions in diagnostics, therapeutics, and the fundamental understanding of prion biology... Read More»
DOI:
10.37421/1747-0862.2023.17.640
Molecular and Genetic Medicine received 3919 citations as per Google Scholar report