Department of Medicine, Chiang Mai University, Chiang Mai, Thailand
Mini Review
Erythromycin Drug Interactions: A Comprehensive Review
Author(s): Chouaia Deeraksa*
Erythromycin, a widely used macrolide antibiotic, is effective against various bacterial infections and also serves as a prokinetic agent for
gastrointestinal disorders. Despite its efficacy, erythromycin is known for significant drug interactions due to its ability to inhibit the cytochrome
P450 (CYP) enzyme system, particularly CYP3A4. These interactions can lead to altered pharmacokinetics of co-administered drugs, resulting in
either reduced therapeutic efficacy or increased toxicity. This comprehensive review explores the pharmacokinetics and pharmacodynamics of
erythromycin, identifies major drug interactions, and discusses the clinical implications of these interactions. Understanding these interactions is
crucial for optimizing therapeutic outcomes and minimizing adverse effects... Read More»
DOI:
10.37421/2475-3211.2024.9.272
Journal of Diabetic Complications & Medicine received 102 citations as per Google Scholar report