Department of Pharmacology, University of Leicester, Leicester LE1 7RH, UK
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Molecular and Epigenetic Mechanisms in Opioid Receptors: Implications for Drug Addiction and Pain Management in Sports
Author(s): Daniela Wagner*
This paper investigates the intricate molecular and epigenetic mechanisms underlying the function and regulation of opioid receptors, with a
particular focus on their implications in drug addiction and pain management within the realm of sports. Opioid receptors play a crucial role in
mediating the effects of endogenous opioids as well as exogenous opioids, such as prescription painkillers or illicit drugs, like heroin. The interplay
between these receptors and their ligands in the central nervous system contributes to both the rewarding effects of opioids and the development of
addiction. Recent advancements in molecular biology and epigenetics have shed light on the complex mechanisms that modulate opioid receptor
expression and function. Epigenetic modifications, including DNA methylation, histone modifications, and non-coding RNAs, have been identified
as c.. Read More»
DOI:
10.37421/2161-0673.2023.13.313
Journal of Sports Medicine & Doping Studies received 1022 citations as per Google Scholar report