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Molecular and Genetic Medicine

ISSN: 1747-0862

Open Access

Darren Sigal

Division of Hematology and Oncology, Scripps Clinic, La Jolla, CA, USA

Publications
  • Review Article   
    Updates in Neuroendocrine Tumor Genomic Studies and Systemic Therapies
    Author(s): Xuemei Ye and Darren Sigal*

    Neuroendocrine tumors (NET) are a mysterious group of malignancies that can form throughout the diffuse neuroendocrine system and produce biological effects distant from their primary location. They have an increasing incidence and can also behave more aggressively than previously recognized. These heterogeneous features have interfered with a more fundamental understanding of tumor biology. Over the past several years, systematic genetic surveys NETs from the major sites of origin have revealed important genomic changes, with potential driver mutations, that have an impact on prognosis and clinical development of targeted therapies. We will take a focused approach in reviewing this data and its impact on clinical medicine... Read More»

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Google Scholar citation report
Citations: 3919

Molecular and Genetic Medicine received 3919 citations as per Google Scholar report

Molecular and Genetic Medicine peer review process verified at publons

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