Journal of Tissue Science and Engineering

Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

Publications

• Mini Review   
  Pancreatic Regenerative Medicine and Stem Cells
  Author(s): David A. Gerber* and Xianwen Yi
  
  Organogenesis of the liver, biliary tree and pancreas is well described in fetal development. Stem/progenitor cells proliferate and subsequently differentiate during early stages of development of the definitive ventral endoderm and these cells contribute to the formation of the foregut. The ongoing debate persists regarding the reactivation of these processes during the postnatal period. Findings regarding this phenomenon have been demonstrated for the liver and biliary tree, and recent studies have demonstrated that this process is also occurring within the pancreas. Despite these observations the mechanisms associated with the processes involved with postnatal organogenesis are not well understood... Read More»
  

  Abstract PDF