Journal of Metabolic Syndrome

Human Bioenergetics and Applied Health Science, Bethel University, Minnesota, United States

Publications

• Research Article   
  Aerobic Glycolysis Couples Metabolic Syndrome to Alzheimer's Disease
  Author(s): Delia Labatt, Cole Smith and Kelly Gibas*
  
  Alzheimer's Disease (AD) is a global epidemic; every 3 seconds someone in the world develops dementia. An estimated 50 million people are living with a disease that cannot be prevented, treated or cured. Without novel breakthroughs, AD is predicted to exceed 130 million by 2050. Pharmaceuticals offer minimal relief with dismal evidence of reversing neurodegeneration. Research focuses on β-amyloid plaques and tau tangles; but, in a clinical trial, medications designed to sop-up toxic proteins in the brain fail to impede neural decline. Instead, plaques and tangles appear to be late-arrivers in the insidious progression of dementia. The recent explosion of comorbid metabolic pathologies (global prevalence of T2DM estimated @ 463 million) invites researchers into a deeper discussion of bioenergetics regulating cognitive impairment and metabolic dysregulation. Age-rela.. Read More»
  

  Abstract PDF