Department of Biochemistry, IBB University, Lapai, Niger State, Niger
Research Article
Anti-Retroviral Therapy and Serum Protein Levels in HIV-1 Seropositive Patients: A Five-Year Retrospective Study
Author(s): Akor Egbunu Shedrack, Musa Haruna, Eneojo-Abah Eleojo Gloria, Yisa Benjamin Nma, Emmanuel Friday Titus, Dickson Achimugu Musa, Joel Ikojo Oguche, Serah Shaibu, Salami Tijani, David Bukbuk and Samuel Eneojo Abah*
Background: Serum proteins designated as liver function biomarkers are used to evaluate patients for hepatic dysfunction. Hepatic effect of Anti-Retroviral Therapy (ART) needs further studies in HIV mono-infected patients. In this study, clinically defined patient datasets were analysed for protein levels in HIV-1 mono-infected seropositive patients with and without ART.
Materials and methods: Data were collected for the study groups, consisting of the control group and HIV-1 mono-infected seropositive patients with and without ART and were analysed statistically for differences among the groups. All subjects in the patient groups attended University of Maiduguri Teaching Hospital, Nigeria for a period of 5 years.
Result: The protein levels on initiation of ART were significantly higher than baseline levels (prior .. Read More»
DOI:
10.37421/vcrh.2020.4.119
Virology: Current Research received 187 citations as per Google Scholar report