Journal of Genetics and DNA Research

Department of Immunology and Oncology, Centro Nacional de Biotecnología, Madrid, Spain

Publications

• Mini Review   
  Genomic Instability and Cancer: Mechanisms and Therapeutic Implications
  Author(s): Diego Fernandez*
  
  Genomic instability is a hallmark of cancer, driving tumorigenesis and tumor evolution. Understanding the mechanisms underlying genomic instability is crucial for developing effective cancer therapies. This mini-review explores the various causes of genomic instability, including DNA damage, replication errors and impaired DNA repair mechanisms. We discuss the implications of genomic instability for cancer development, progression and therapeutic resistance. Furthermore, we highlight emerging therapeutic strategies targeting genomic instability pathways for cancer treatment... Read More»
  DOI: 10.37421/2684-6039.2024.8.196

  Abstract HTML PDF