Department of Neurology, Oxford University Hospitals NHS Trust, UK
Research
A Systematic Review of the Psychiatric Associates of Nf2- Schwannomatosis and How These Compare Against Other Neuro-Cutaneous Disorders
Author(s): Christopher Lucas*, Ivan Koychev, Dorothy Halliday and Allyson Parry
Neurofibromatosis type 2 (NF2), now called NF2-schwannomatosis is a debilitating genetic syndrome that can cause widespread physical impairment such as deafness, visual impairment, and limb weakness. The molecular and physical manifestations of NF2 have been well described, and several studies have demonstrated the negative impact of NF2 on Quality of Life (QOL). In contrast, few studies have addressed whether there are specific psychiatric associates of NF2-schwannomatosis. This current review summarises what is known about psychiatric features associated with NF2-schwannomatosis. For comparison, the prevalence of similar features in other genetically distinct neuro-cutaneous disorders is also briefly described. It is hoped that the information provided in this review will highlight potential areas for future research in NF2-schwannomatosis, with the subsequent aims of optimizing hol.. Read More»
DOI:
10.4172/2329-6895.10.1.474
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