Research and Reports in Medical Sciences

King Abdulaziz University, Saudi Arabia

Publications

• Extended Abstract   
  Molecular Pathology 2020: Targeting Tumor Microenvironment and Epigenome; Diagnostic, Prognostic and Therapeutic Implications- Dr.Imrana Tanvir - King AbdulAziz University
  Author(s): Dr.Imrana Tanvir
  
  The dynamic interactions of cancer cells with their microenvironment consisting of stromal cells (cellular part) and extracellular matrix (ECM) components (non-cellular) is essential to stimulate the heterogeneity of cancer cell, clonal evolution and to increase the multidrug resistance ending in cancer cell progression and metastasis. The reciprocal cell-cell/ECM interaction and tumor cell hijacking of non-malignant cells force stromal cells to lose their function and acquire new phenotypes that promote development and invasion of tumor cells. Understanding the underlying cellular and molecular mechanisms governing these interactions can be used as a novel strategy to indirec.. Read More»
  

  Abstract PDF