Department of Nephrology, Hypertension and Family Medicine, Medical University of Lodz, 90-549 Lodz, Poland
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Mechanisms of Hyperkalemia in Chronic Kidney Disease and Strategies for Management
Author(s): Dustin Tamargo*
Hyperkalemia, defined as an elevated serum potassium level, is a common and potentially life-threatening complication of Chronic Kidney
Disease. As kidney function declines, the ability to excrete potassium diminishes, leading to its accumulation in the blood. Hyperkalemia can
result in severe cardiac arrhythmias and muscle weakness, necessitating prompt and effective management. This article reviews the underlying
mechanisms of hyperkalemia in CKD, including impaired renal potassium excretion, altered cellular distribution of potassium, and the impact of
medications such as renin-angiotensin-aldosterone system inhibitors. Additionally, we discuss various strategies for managing hyperkalemia in
CKD patients, ranging from dietary modifications and potassium-binding agents to the use of novel pharmacological treatments. Understanding
these mechanisms and manageme.. Read More»
DOI:
10.37421/2161-0959.2024.14.514
Journal of Nephrology & Therapeutics received 784 citations as per Google Scholar report