Hepatology and Pancreatic Science

Department of Chronic Disease Epidemiology, University Hospital Tübingen, 72076 Tübingen, Germany

Publications

• Mini Review   
  Unlocking Emerging Biomarkers for Early Detection of Hepatocellular Carcinoma
  Author(s): Elisa Thomas*
  
  Hepatocellular carcinoma is one of the most prevalent types of liver cancer, with a high mortality rate worldwide. Early detection of HCC is crucial for effective treatment and improved patient outcomes. While conventional diagnostic methods like imaging and biopsy remain primary tools, emerging biomarkers offer promising avenues for early detection, enabling timely intervention. This article explores recent advancements in biomarkers for the early detection of HCC. Alpha-Fetoprotein (AFP) has long been utilized as a biomarker for HCC screening. However, its sensitivity and specificity are suboptimal, leading to the exploration of novel biomarkers to complement AFP in early detection efforts. Recent studies have investigated AFP-L3 and des-gamma-carboxy prothrombin isoforms of AFP, which have shown improved performance in detecting early-stage HCC. MicroRNAs ar.. Read More»
  DOI: 10.37421/2573-4563.2024.8.281

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