Department of Biology, Kaplan Medical Institute, The Hebrew University, Jerusalem 9190501, Israel
Mini Review
Female Carriers of Germline Pathogenic
Author(s): Evron Eitan*
Females with germline BRCA1/BRCA2 (BRCA) P/LPV are given a tight surveillance programme from the ages of 25 to 30 that includes risk-reduction
interventions and aims to detect certain cancer types early. Numerous national and international surveillance standards have been created and
updated over the past 20 years by a wide range of countries from all over the world. Between January 1, 2015 and May 1, 2022, we searched for
regulations that had been published. A few notable examples include variations in primary prevention recommendations, mammography screening
in young (30 years) carriers, MRI screening in carriers older than 65 years, any breast imaging after a risk-reducing bilateral mastectomy, while
pregnant or nursing and hormone replacement therapy. Beyond official advice, BRCA carriers' concerns also centre on fertility preservation, the
management of me.. Read More»
DOI:
10.37421/2684-494X.2022.7.43