Department of Radiology, Rabta University Hospital Center, Tunis, Tunisia
Case Series
Clinical Features and Management of Langerhans Cell Histiocytosis: A Case Series
Author(s): Tayssir Ben Achour*, Maysam Jridi, Ines Naceur, Monia Smiti, Fatma Said, Mohamed Habib Houman and Eya Azouz
Background: Langerhans histiocytosis (LCH) is a rare hematopoietic disease characterized by clonal expansion of myeloid precursors differentiating
into CD1a+/CD207+ histiocytes infiltrating different organs. The study aimed to report the clinical features such as the onset presentation and
systemic lesions of LCH among Tunisian adult patients and the therapeutic management of the disease with onboard medications.
Methods: A descriptive, retrospective and monocentric study taking place in the internal medicine department of Rabta University Centre.
Results: The study included eight patients. The median age at the diagnosis was 35 years. The mean duration between the first symptoms and the
diagnosis was 17 months. The first most consulted doctors were neurologists. The revealing symptoms were neurological in .. Read More»
DOI:
10.37421/2157-7099.2023.14.689
Journal of Cytology & Histology received 2334 citations as per Google Scholar report