Journal of Hypertension: Open Access

Department of Cardiology, Johns Hopkins Medical Institutions, Baltimore, MD, USA

Publications

• Research Article   
  Blockage of Angiotensin 2 Receptor-1 Effects Not Only on Stress-induced Myocardial Dynamics but on Circulating Cathecolamins in Hypertensive Patients
  Author(s): Nurettin Yeral* and Fatih Yalcin
  
  We aimed to investigate alterations at plasma norepinephrine (NE) levels during rest and exercise and to evaluate tissue Doppler imaging (TDI) parameters in patients with essential hypertension after 6 months from treatment with olmesartan 20 mg. Fourty patients were included in the study. Rest and exercise plasma NE levels were evaluated before and after olmesartan 20 mg treatment. Plasma NE levels were studied by HPLC (high performance liquid chromatography) device. Nevertheless, we examined whether there was a relationship between TDI parameters and plasma NE levels. After 6 months from treatment with olmesartan, rest plasma NE levels (p<0.05) and exercise plasma NE levels (p<0.001) were significantly decreased. Left ventricular mass index (LVMI) and septal myocardial performance index (MPI) were significantly decreased. Systolic septal myocardial velo.. Read More»
  DOI: 10.37421/2167-1095.2022.11.362

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