Journal of Nephrology & Therapeutics

Department of Internal Medicine, University of the Witwatersrand, Johannesburg, South Africa

Publications

• Opinion   
  Formulation and Blood?brain Barrier Transport of Cannabidiol-loaded Nanovesicles
  Author(s): Frank Edet**
  
  Nanovesicles have emerged as a promising drug delivery system for enhancing the bioavailability and therapeutic potential of various pharmacological agents, particularly those targeting the central nervous system. Cannabidiol, a non-psychoactive cannabinoid, has demonstrated neuroprotective, anti-inflammatory, and anticonvulsant properties, making it a promising candidate for treating neurological disorders such as epilepsy, multiple sclerosis, and neurodegenerative diseases. However, its therapeutic efficacy is often limited by poor solubility, rapid metabolism, and difficulty in crossing the blood-brain barrier. The development of cannabidiol-loaded nanovesicles aims to overcome these limitations by improving drug stability, enhancing transport across biological barriers, and providing sustained release wit.. Read More»
  

  Abstract PDF