Gopinath Subramaniyam

Department of Pharmaceutics, Sri Ramachandra Faculty of Pharmacy, Sri Ramachandra Institute of Higher Education and Research (DU), Porur, Chennai, Tamil Nadu, India

Publications

Research Article
An Effective Liposomal Gel Preparation for the Long-lasting Herbal Mosquito Repellent
Author(s): T. M. Suruthelaya, Kaviya Suresh, K. K. Suriya Prakaash, S. Nagalakshmi, A. C. Niranjanasree, Gopinath Subramaniyam, J. Srikanth, P. Krishnan and Anbarasan Balu*

Herbal mosquito repellent is a promising alternative to overcome the drawbacks of conventional mosquito repellents containing N, N-diethyl metatoluamide. The liposomal gel has a propensity for keratinizing the skin's horny layer and can penetrate deeper into the skin for enhanced absorption and is therapeutically effective and less toxic than other topical dosage forms, resulting in prolonged and controlled extract release. Vitex negundo (Chaste tree) leaves were dried and mechanically powdered. The powder was extracted with ethanol and distilled water (1:1), then the solvent was removed, dried using a lyophilization process, and stored. The phytochemical and composition analysis of the plant extract was done. The hydration process is carried out at a temperature of 40°C. Liposomal gel was prepared using the thin film hydration methods. A suitable base.. Read More»
DOI: 10.37421/2472-0992.2024.10.282

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