Faculty of Biology, Medicine and Health, Division of Neurosciences and Experimental Psychology, The University of Manchester, UK
Research Article
More Evidence of Altered Microflora in Patients with Autism Spectrum
Disorder (ASD): A Controlled Analysis of qPCR Stool Results in 147 Cases of
ASD
Author(s): Mansab F, Neil J and Goyal D*
Aim: Autism Spectrum Disorder (ASD) is a prevalent neuropsychiatric condition affecting a person’s ability
to interact and socialize. It varies in severity, but the majority are unable to work or develop partnerships. There
are currently no treatments. Microflora abnormalities have been investigated in relation to the neuropsychiatric
manifestations in ASD. Various abnormalities have been identified, and to date there are no refutation studies
discoverable.
Methods: A total of 147 patients with ASD had undergone quantitative Polymerase Chain Reaction (qPCR)
stool analysis at initial presentation and had been free from antibiotics for the previous three months. The proportion
of firmicutes to bacteriodetes phyla were calculated in a percentage ratio. Controls were taken from patients who
had attended the outpat.. Read More»
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