Department of Nephrology, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain
Research Article
High Sensitivity Cardiac Troponin I, a Possible Biomarker of Diastolic Dysfunction in Asymptomatic Patients in Hemodialysis
Author(s): Paz Castro Fernández*, Carmen Vozmediano Poyatos, Martin Negreira Caamaño, Daniel Campos Valverde, Luis Piccone Saponara, Guillermo Ferrer García, Gloria García Conejo, Roger Cox Conforme, Marcos Santos-Olmo Montoya and Agustín Carreño Parrilla
Objective: There are clinical conditions with histological evidence of non-ischemic myocardial necrosis that are associated with elevated troponin levels, such as the structural and functional alterations of the Left Ventricle (LV) that occur in Left Ventricular Diastolic Dysfunction (LVDD). We analyzed the relationship between the ultrasensitive Troponin I biomarker (TnI-US) and LVDD in a cohort of asymptomatic Hemodialysis (HD) patients.
Methods: Descriptive cross-sectional study including 80 patients. Categorical variables were compared using Chi2 test, and quantitative variables
were compared with Student's t-test or Mann-Whitney U-test. ROC curve to determine the predictive value of TnI-US levels for LVDD. Logistic regression analysis to determine the factors independently associated with LVDD.
Results: The me.. Read More»
DOI:
10.37421/2161-0959.2023.13.461
Journal of Nephrology & Therapeutics received 784 citations as per Google Scholar report