Department of Oncology Radiotherapy, CHU Ibn Rochd, Casablanca, Morocco
Case Report
Leptomeningeal Metastasis from Castration-resistant Prostate Cancer: A Case Report
Author(s): Hanan Rida*, H. Zaine, H. Jouhadi, D. Bentaleb, M. Sabiri and F. Essodegui
Leptomeningeal carcinomatosis is an exceedingly rare complication of prostate cancer. However, its incidence may increase as prostate cancer
patients survive longer with new therapies even after castration resistance. The clinical presentation is varied and nonspecific. The diagnosis of
leptomeningeal metastatic disease is made either by identifying malignant cells in cerebrospinal fluid or by gadolinium-enhanced MRI. Several
treatments, including radiation therapy, intrathecal chemotherapy, steroids, debulking surgery, and best supportive care have been suggested.
Although, the prognosis is extremely poor not exceeding weeks. We report a case of leptomeningeal carcinomatosis in a 64-year-old patient with
metastatic castration-resistant prostate cancer with a review of the literature... Read More»
DOI:
10.37421/2684-4915.2022.6.199
Clinical and Medical Case Reports received 40 citations as per Google Scholar report