Department of Science, Northeast Forestry University, Harbin 150040, China
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Development and Characterization of Human Umbilical Cord Perivascular Cells with Alkaline Phosphatase Activity
Author(s): Haixia Chen*
Human Umbilical Cord Perivascular Cells (HUCPVCs) represent a promising source of multipotent stem cells with potential applications in
regenerative medicine and tissue engineering. This study focuses on the development and characterization of HUCPVCs with a specific emphasis
on their Alkaline Phosphatase (ALP) activity, a critical marker of osteogenic differentiation. HUCPVCs were isolated from human umbilical cords
and characterized for their phenotype, differentiation potential and ALP activity using various assays and techniques. Our findings demonstrate
that HUCPVCs exhibit robust ALP activity, indicative of their capacity for osteogenic differentiation. Furthermore, we elucidate the molecular
mechanisms underlying ALP regulation in HUCPVCs, providing insights into their therapeutic applications in bone regeneration and repair. This
study enhances our unde.. Read More»
DOI:
10.37421/2952-8127.2024.8.174
Research and Reports in Medical Sciences received 13 citations as per Google Scholar report