Journal of Hypertension: Open Access

Department of Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, Kaohsiung 833, Taiwan

Publications

• Mini Review   
  Perinatal Cardiovascular Features and Angiotensin System Expressions in Maternal Preeclampsia
  Author(s): Heyansh Kreiselukas
  
  Preeclampsia remains a significant cause of maternal and perinatal morbidity and mortality globally, characterized by hypertension and proteinuria arising after 20 weeks of gestation. This comprehensive review explores the intricate interplay between perinatal cardiovascular features and alterations in the Renin-Angiotensin System (RAS) in maternal preeclampsia. Preeclamptic pregnancies are marked by systemic vascular dysfunction, including impaired vasodilation and increased vascular resistance, which contribute to elevated maternal blood pressure and compromised placental perfusion. Mechanistically, dysregulation of the RAS, with heightened angiotensin II levels and altered expression of angiotensin receptors, plays a pivotal role in the pathophysiology of preeclampsia. The review synthesizes current evidence on the association between maternal preeclampsia a.. Read More»
  DOI: 10.37421/2167-1095.2024.13.465

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