Journal of Cancer Clinical Trials

Department of Palliative Care, Vanderbilt University Medical Center, Nashville, TN, USA

Publications

• Case Report   
  Efficacy of Cingulotomy for Refractory Malignant Cancer Pain, A Case Series
  Author(s): Hillary Fitzgerald*, Harkiran Sandhu, Claudio Tombazzi, Danika Paulo, Stacey Tillman, Sumathi Misra, Hamid Shah and Mohana Karlekar
  
  Purpose: Poorly controlled pain is a significant quality of life issue for patients with advanced cancer. Patients often suffer from uncontrolled pain or intolerable side effects of treatment despite receiving multi-modal care with stepwise escalation of opioids. Interventional procedures impacting central pain pathways have demonstrated promise in treating pharmacologically intractable cancer pain and may be underutilized, especially in patients with escalating opioid use. The aim of this study was to assess effectiveness of bilateral anterior cingulotomy a minimally invasive neurosurgical procedure in patients with refractory malignant cancer pain through describing opioid use trends pre- and post-procedure and by comparing pain scores. Methods: This is a retrospective review of a case series of six patients with refractory malignant pain .. Read More»
  

  Abstract PDF