Journal of Food & Industrial Microbiology

Department of Gastroenterology, Nara Medical University, Kashihara, Nara, Japan

Publications

• Review Article   
  The Gut affects Pathophysiology and Management of Diabetes Mellitus Type 2: The Recent Messages from Intestine and Gastrointestinal Microbiota
  Author(s): Hiroshi Fukui*
  
  The number of diabetic patients rapidly increased in the world constituting a serious health problem. Daily life alterations such as high-fat high-sugar diet and insufficient physical exercise augment diabetes risk. Long-lasting low-grade inflammatory reactions in obese patients with metabolic syndrome are considered as an important role in the occurrence and advance in the stage of type 2 diabetes. Emerging clinical and experimental evidence reveals that gut dysbiosis, intestinal barrier disturbance and following metabolic endotoxemia are firmly related to the low-grade inflammatory, insulin resistance and resultant cardiovascular complications in patients with type 2 diabetes. Gut microbiome transmitted from mother to child at birth is deeply affected by dietary habits in life thereafter. In the feces of type 2 diabetics, relatively frequent abundance in endotoxin producing gram-neg.. Read More»
  DOI: 10.37421/2572-4134.2024.10.229

  Abstract HTML PDF