Journal of Health & Medical Informatics

Department of Pharmacology, SUNY Upstate Medical University, Syracuse, USA

Publications

• Review Article   
  A Review on Alcoholic Hepatitis
  Author(s): Hong Lu*
  
  Alcoholic hepatitis is a significant wellbeing and monetary weight around the world. Glucocorticoids (GCs) are the main first-line drugs prescribed to treat serious alcoholic hepatitis (sAH), with restricted transient adequacy and huge incidental effects. In this survey, I sum up the significant advantages and results of GC treatment in sAH and the likely basic components. The survey of the writing and information mining plainly show that the hepatic motioning of glucocorticoid receptor (GR) is uniquely debilitated in sAH patients. The disabled GR flagging causes hepatic downguideline of qualities fundamental for gluconeogenesis, lipid catabolism, cytoprotection, and against irritation in sAH patients. The viability of GCs in sAH might be undermined by GC opposition or potentially GC's extrahepatic aftereffects, especially the results of digestive epithelial GR .. Read More»
  DOI: 10.37421/2157-7420.2022.13.426

  Abstract HTML PDF