Ruikang Hospital Affiliated to Guangxi University of traditional Chinese Medicine, nanning, guagnxi, China
Research
Electro-Acupuncture treatment Promotes Regeneration and Recovery of Spinal Cord Injured Nerve by Regulating HIF-1α/VEGF Signal Pathway
Author(s): Weibing-Wei, Lingyao-Zhou, Hongsheng-Zhang, Zhengxin-Li, Yu-Yang and Binbin-Zhou*
Objective: The present study aimed to explore the effect of Electro-acupuncture (EA) on the mechanism of nerve
regeneration and recovery in spinal cord injury rats by interfering with the expressions of factors associated with
HIF-1α/VEGF signaling pathway, covering HIF-1α, VEGF, PKA, Synapsin I, CaMKII as well as BDNF.
Methods: 120 SD female rats after achieving the successful modeling of spinal cord injury were randomly split
into Jia ji EA group (EA-1 group), Yang ming EA group (EA-2 group), as well as Sham group(n=48 per groups);
subsequently, the rats were split into 5 subgroups (1-5week group, n=8 per subgroups). EA treatment was
performed on the 3rd day after the mice achieved the modeling, and specimens were taken at different time points
after the treatment. BBB score was employed to assess the vari.. Read More»
Journal of Spine received 2022 citations as per Google Scholar report
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