Department of Surgery, University of Connecticut, Farmington, Belgium
Mini Review
Epigenetic Regulator Changes in Pancreatic Cancer
Author(s): James Rodrigue*
Pancreatic cancer is one of the deadliest cancers, with a five-year survival rate of less than 10%. Despite advances in the treatment of other
cancers, pancreatic cancer remains a difficult disease to treat due to its aggressive nature and late diagnosis. In recent years, there has been
increasing interest in the role of epigenetics in the development and progression of pancreatic cancer. Epigenetics refers to modifications of DNA
and histones that regulate gene expression without altering the underlying genetic code. Alterations in epigenetic regulators can lead to aberrant
gene expression, resulting in the development and progression of cancer. In pancreatic cancer, several epigenetic regulators have been found to
be deregulated, including DNA methylation, histone modifications and non-coding RNAs... Read More»
DOI:
10.37421/2472-1247.2023.9.250
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