Department Chemical & Biomedical Engineering, Florida State University, Tallahassee, FL 32310, USA
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Physicochemical and Biological Characterization of Nanofibrous ?-Polycaprolactone Matrices with Nano-hydroxyapatite and Humulus lupulus L. Extract for Oral Applications
Author(s): Jeanne Amy*
This study presents the physicochemical and biological characterization of nanofibrous ε-polycaprolactone (PCL) matrices incorporated with nano-
Hydroxyapatite (nHA) and Humulus lupulus L. (hops) extract for potential oral applications. The electrospun Nanofibrous matrices were fabricated
using a blend of ε-polycaprolactone polymer, nano-hydroxyapatite, and hops extract. Physicochemical analyses including Scanning Electron
Microscopy (SEM), Fourier-Transform Infrared Spectroscopy (FTIR), and X-Ray Diffraction (XRD) were performed to assess the morphology,
chemical composition, and crystallinity of the matrices. Biological characterization involved in vitro evaluation of cytocompatibility using Human
Gingival Fibroblasts (HGFs) and antimicrobial activity against oral pathogens. The results demonstrate the successful fabrication of nanofibrous
mat.. Read More»
DOI:
10.37421/2155-9538.2024.14.414
Journal of Bioengineering & Biomedical Science received 307 citations as per Google Scholar report