Office of HIV/AIDS, Bureau for Global Health, United States Agency for International Development, Washington, DC, USA
Mini Review
Transitioning and Sequencing Paediatric Antiretroviral Treatment
Regimens in the Dolutegravir Era: Emerging Questions
and Considerations
Author(s): Jeffrey M. Samuel, Adrian Gardner, Natella Y. Rakhmanina and Christine Y. Malati*
For patients failing a dolutegravir (DTG)-based regimen, understanding a patient's personal history of antiretroviral (ARV) exposure will become increasingly important. With the universal initiation and switch to DTG-based regimens for currently stable patients, the terminology of first-, second- and third-line antiretroviral therapy (ART) is no longer applicable. The adoption of a patient centric approach will ensure that patients receive the most appropriate regimen to achieve virologic suppression. This article proposes a few recommendations for adopting a patient-centric approach to HIV treatment... Read More»
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