Department of Gastrointestinal Surgery, Clinical Medical College, Dalian Medical University, Dalian, P.R. China
Case Report
Secondary Multiple Cutaneous Metastases from Primary Gastric Signet-Ring Cell Adenocarcinoma
Author(s): Jian-Jiao C and Zhao W*
A 60-year-old man was diagnosed with gastric cancer by endoscopy in our cancer center. Preoperative CT scan
showed thickening of the cardia and enlarged lymph nodes in hepatogastric space. Consequently, he accepted
total gastrectomy and Roux-en-Y reconstruction. Immunohistochemical detection showed intense positivity for
GST-n and Pgp antibodies and negativity for EGFR, ERCC1, P53, Ki67 and HER-2. Surprisingly, within one month,
the patient had multiple asymptomatic cutaneous nodules in the left neck, right subclavian, left armpit, left upper
abdomen, lower abdomen, right groin and lumbodorsal region. Abdominal CT scan showed a 22 × 22 mm highdensity
lesion in the splenorenal space, as well as cutaneous nodules in the left upper abdomen, lower abdomen
and right groin. Histopathologic examination of cutaneous biopsy showed a poorly differentiated signe.. Read More»
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