Journal of Inflammatory Bowel Diseases & Disorders

Department of Specialized Clinical Sciences and Odontostomathology, University Polytechnic of Marche, Ancona, Italy

Publications

• Mini Review   
  Decoding Immune System Dysfunction: Unveiling its Role in Inflammatory Bowel Diseases
  Author(s): Julio Brabec*
  
  Immune system dysfunction plays a pivotal role in the pathogenesis of Inflammatory Bowel Diseases (IBD), including Crohn's disease and ulcerative colitis. This article explores the intricate mechanisms underlying the dysregulation of the immune system in IBD and its impact on gastrointestinal inflammation. The review delves into the immunological factors triggering chronic inflammation, genetic predispositions, and the interplay between the innate and adaptive immune responses. Furthermore, it examines the role of gut microbiota in influencing immune system dysfunction and its contribution to disease progression. Therapeutic strategies targeting immune dysregulation are also discussed, including immunomodulators, biologic therapies, and potential future prospects. By understanding the complexities of immune system dysfunction in IBD, new avenues for diagnosis and treat.. Read More»
  DOI: 10.37421/2476-1958.2023.8.175

  Abstract HTML PDF