Journal of Clinical Case Reports

Department of Medicine, University of Florida, Florida, USA

Publications

• Case Report   
  Acute Myocardial Infarction Following 5-Fluorouracil Treatment
  Author(s): Jose Rivas Rios*, Melissa Oye, Yixin Zhang, Fabiana Rollini and Kadeja Esmail
  
  A 62-year-old male with recently diagnosed stage IV pancreatic cancer was started on chenotherapy with 5-Fluourouracil. Shortly after initiation, he suffered cardiac arrest. We will review the proposed pathophysiology of 5-Fluourouracil cardiotoxicity, the reported incidence, treatment, and the antidote for 5-Fluorouracil overdose or toxicity. Myocardial infarction is an adverse cardiac reaction associated with 5-fluorouracil (5-FU). Data on the incidence, risk, and prognosis of 5-FU-related myocardial infarction are limited. Fluorouracil (5-FU) is the most commonly proposed chemotherapy drug for colorectal cancer. Cardiogenic side effects such as autopsy arterial vessels seizures, ventricular arrhythmias, and cardiac ischemia are also rare... Read More»
  DOI: 10.37421/2165-7920.2022.12.1512

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