Pulmonary & Respiratory Medicine

Department of Internal Medicine, College of Kobe University, Chuo-Ku, Kobe, Japan

Publications

• Research Article   
  Long−Term Prognosis of Connective Tissue Disease Associated Pulmonary Arterial Hypertension
  Author(s): Kazuhiko Nakayama*
  
  Objective: Pulmonary Arterial Hypertension (PAH) is a progressive disease characterized by increased pulmonary arterial pressure and pulmonary vascular resistance that can lead to right heart failure. Connective Tissue Disease-Associated PAH (CTD-PAH) often has a worse outcome than idiopathic or Hereditary PAH (I/HPAH), suggesting the presence of non-PAH factors that may affect the prognosis of CTD-PAH patients. This study aimed to identify prognostic factors for CTD-PAH. Methods: Medical records from the April 1999 through November 2014 period were reviewed to determine the time from treatment initiation to occurrence of a clinically worsening event (hospitalization for PAH exacerbation, progression to WHO Functional Class III or worse, decrease in 6-min walking distance by ≥ 15% from baseline, initiation of parenteral prostanoid therapy.. Read More»
  DOI: 10.37421/2157-7145.2022.12.619

  Abstract HTML PDF