Chemical Sciences Journal

Department of Pharmaceutical Chemistry, National Organization for Drug Control and Research, Giza, Egypt

Publications

• Research   
  Microwave Synthesis, Spectral, Thermal, and Pharmacological Evaluation of Some Metal Complexes Containing Benzene Sulfonyl Thiourea Moiety
  Author(s): Hassan AM, Abd El-Wahab ZH, Salman A A, Abd El-Rahman NM, Salama TAM, El-Tantawy ASM and Khalid MW*
  
  Synthesis and characterization of organic ligand N-(2-chloro phenyl)-N’ benzenesulfonyl thiourea (H2L1) was described. The formed ligand incorporated several potential donor sites, making it a versatile complexing agent with metal ions due to the presence of the sulfonyl and thiourea groups, each solely may act as a key constituent of many biologically active species. In this work, we present the synthesis of Pt (II), Pd (II) and Au (III) metal complexes and their coordination behavior towards the unsymmetrical organic ligand (H2L1) using microwave-assisted irradiation. The microwave approach provides clean, shorter reaction times and enhancements in yields. The prepared metal complexes have been characterized by elemental analysis, FT-IR, 1HNMR, UV-Vis, thermal analysis and magnetic susceptibility. They were tested for their antibacte.. Read More»
  DOI: 10.37421/2150-3494.2020.11.211

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