Journal of Clinical Case Reports

Department of Clinical Pharmacy, Tel-Aviv Sourasky Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

Publications

• Case Report   
  Tigecycline−Induced Triad of Adverse Effects − Acute Pancreatitis, Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) and Thrombocytopenia: A Rare Case Report
  Author(s): Khalil Zahalka* and Tsvi Gregory Avishai
  
  Reports about Tigecycline-induced acute pancreatitis are raising, Tigecycline-induced thrombocytopenia and hypersensitivity reactions are also fairly reported leading to severe clinical complications. We report a rare case of a triad adverse effects associated with Tigecycline treatment in a 5-year-old boy who received Tigecycline for treatment of disseminated mycobacterium abscessus within three months. Tigecycline was a leading cause for all three adverse effects especially acute pancreatitis based on the Naranjo adverse drug reaction probability scale, adverse effects were addressed by a multidisciplinary team and even discontinuation of Tigecycline was done twice with a desensitization re-challenge protocol. Clinicians should be aware of these possible adverse effects especially acute pancreatitis and mainly in high-risk patients... Read More»
  DOI: 10.37421/2165-7920.2023.13.1545

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