Department of Pharmacy, BM College of Pharmaceutical Education & Research, Indore, India
Research
Formulation, Development and Evaluation of Paracetamol Tablet by Moisture Activated Dry Granulation (MADG) Process
Author(s): Arpit Gawshinde*, Dharmendra Solanki, Komal Tikariya, Umesh Atneriya and Pushpanjali Chaurasia
Background: Paracetamol, also known as acetaminophen, is a painkiller that is popular throughout the world because it does not irritate the
stomach. Paracetamol was first discovered to have both analgesic and antipyretic properties in the late nineteenth century. The aim of present
work was to Formulate, develop and evaluate Paracetamol Tablets by Moisture Activated Dry Granulation (MADG) process to short manufacturing
time and process variables as compared with convention process.
Method: Colloidal anhydrous silica is used in the formulation to absorb the extra moisture present in the MADG process formulation. A total number
of five formulations were prepared and weight of all tablets kept constant. i.e. 595 mg.
Result: All the formulations resulted in acceptable limit. The final batch F3 (contained PV.. Read More»
DOI:
10.37421/2952-8100.2024.07.467
Spanish 
Chinese 
Russian 
German 
French 
Japanese 
Portuguese 
Hindi 