Molecular and Genetic Medicine

Department of Science, University of California, Los Angeles, USA

Publications

• Review   
  The Components of Lifestyle Adjustments in Hypertension Guidelines Which Consider Gene and Environmental Interactions
  Author(s): Krista Ritchie*
  
  Lifestyle choices and genetics are two types of risk factors for hypertension. Heritability estimates for BP range from 34–67%, according to studies of twins and family history. About 20% of the population variation in BP has been explained by the most recent paper on BP GWAS. Due to violations of shared environment assumptions, poor phenotyping practices in control cohorts, failure to account for epistasis, gene-gene and geneenvironment interactions and other non-genetic sources of phenotype modulation, twin studies may have overestimated heritability. GWAS may have underestimated heritability. The proposals of hypertension rules in significant nations comprise of the accompanying components: Dietary sodium reduction, weight loss, increased physical activity, quitting smoking and moderate alcohol consumption are some of the other strategies. Beyond race .. Read More»
  DOI: 10.37421/1747-0862.2022.16.581

  Abstract HTML PDF