Hallands Djursjukhus, Kungsbacka Hästklinik, Älvsåkers Byväg 20, SE 434 95 Kungsbacka, Sweden
Case Report
A Novel Treatment Combination of Sildenafil, Mepivacaine and Glucose with Disease Modifying Properties, In a Pony with Lameness Associated Osteoarthritis: A Case Report
Author(s): Eva Skiöldebrand*, Kristin Abrahamsson Aurell, Saritha Adepu, Anders Lindahl and Elisabeth Hansson
Today no biomarkers reflecting joint tissue destruction or Disease-Modifying Osteoarthritis Drugs (DMOADs) are available on the market. This
case report decscribes a new pharmaceutical drug combination consisting of Sildenafil, Mepivacaine and Glucose (SMG) used for intra-articular
treatment of lameness associated osteoarthritis of the right distal interphalangeal joint in a nine-year-old Swedish pony. The pony had a history
of moderate lameness during five months and were treated with intra articular corticosteroids three times without any recovery of lameness (visit
1-5). Clinical lameness examinations, including intra articular anaesthesia, radiological examination, standing low-field MRI and quantification of
biomarkers for cartilage and bone degradation (COMP156 and BGN262) in synovial fluid and serum was performed over a period of 24 mon.. Read More»
DOI:
10.37421/2165-7920.2023.13.1576
Journal of Clinical Case Reports received 1345 citations as per Google Scholar report