Forensic Scientific Assistant, DNA Division, State Forensic Science Laboratory, Rajasthan, Jaipur, India
Research Article
Comparison of Four Different DNA Extraction Methods and their Compatibility with Present-day STR Based Capillary Electrophoresis Typing
Author(s): Neha Gupta, Rajesh Kumar and Kunwar Veer Vikram Srivastav*
Currently, Short Tandem Repeats (STRs) based forensic DNA typing technology is being internationally used in solving a diverse range of forensic
cases, and presently, forensic DNA tests employ Polymerase Chain Reaction (PCR) and Capillary Electrophoresis (CE) based fragment analysis
methods to detect length variation in STRs. The quality of STR-based DNA profiles from challenging samples depends on the yield and quality of
DNA. The yield of DNA predominantly depends upon the method used for DNA extraction. DNA extraction is the first and perhaps most important
step in any Forensic DNA analysis. Any specific method can never be thought of to be convenient for all types of samples. Still, Phenol Chloroform
Isoamyl Alcohol (PCIA) method which is called the organic extraction method has been proven to be useful for a wide variety of forensic samples
ranging from th.. Read More»
DOI:
10.37421/2157- 7145.2022.13.492
Journal of Forensic Research received 2328 citations as per Google Scholar report