Department of Pharmacy, Jawaharlal Nehru Technological University, Hyderabad, Telangana, India
Opinion
Treatment of IGFs Development
Author(s): Lakshmi Bhai*
The proteins known as insulin-like growth factors (IGFs) share a lot of similarities with insulin in their sequence. IGFs are a component of a sophisticated
system used by cells to interact with their physiologic environment. Two cell-surface receptors (IGF1R and IGF2R), two ligands (IGF-1 and
IGF-2), a family of seven high-affinity IGF-binding proteins (IGFBP1 to IGFBP7), and associated IGFBP degrading enzymes, collectively known as
proteases, make up this intricate system, which is frequently referred to as the IGF "axis." IGF-1 plays a role in controlling various aspects of brain
development, such as neurogenesis, myelination, synaptogenesis, dendritic branching, and neuroprotection following neuronal damage. IGF-I
serum levels that are greater in children have been linked to a higher IQ. IGF-1 regulates apoptosis, which influences how the cochlea deve.. Read More»
DOI:
10.37421/2684-494X.2022.7.53
Spanish 
Chinese 
Russian 
German 
French 
Japanese 
Portuguese 
Hindi 