Department of Biological Sciences, University of Manitoba, Winnipeg, MB R3T 2N2, Canada
Mini Review
Effects of TFM and Niclosamide on the Transcriptome and Putative Detoxification Pathways in a Lampricide−Tolerant Teleost
Author(s): Lawre Serti*
It appears that lampreys have a different detoxification capacity than bony fishes, particularly teleosts, which accounts for TFM's superiority against
lampreys. Notwithstanding, the general systems of resilience to the TFM and niclosamide blend and the components of niclosamide poisonousness
all alone are inadequately perceived, particularly among non-target fishes. Here, we identified specific mRNA transcripts and functional processes
that responded to niclosamide or a TFM using RNA sequencing: bluegill (Lepomis macrochirus) contain a niclosamide mixture. Bluegill were
exposed to either TFM or niclosamide: niclosamide combination, alongside a period matched control gathering, and gill and liver tissues were
inspected at 6, 12, and 24 h. We summed up the entire transcriptome designs through quality metaphysics (GO) term improvement and through
differential art.. Read More»
DOI:
10.37421/2795-5833.2023.13.491